Xinhua News Agency, Beijing, August 21. A review article on the origin of the new coronavirus written by scientists from multiple countries was published in the US magazine Cell this week. This is an important judgment made by professionals in this field on the issue of traceability based on existing scientific evidence. The article Cinema strongly refuted the “lab leak” conspiracy theory advocated by some American politicians, and pointed out that cross-species transmission from animals to humans is the most likely source of the new coronavirus. Cinema
More than 20 mainstream scientists in the world have co-written this article, including KomiksLove from the Mary Bashir Institute of Infectious Diseases and Biosafety, University of Sydney, Australia, BabaylanDward Holmes, Department of Human Genetics, University of Utah, and University of Saskatchewan, Canada. href=”https://comicmov.com/”>KomiksEngera Rasmussen who studies vaccines and infectious diseases, David Robertson of the Center for Virology Research at the University of Glasgow, UK, etc. The preprint of the article was published in early July on the open scientific data platform ZenodoKomiks.
The article says that no epidemic in human history was caused by the escape of a new virus, and there is no data that before the outbreak of the new coronavirus, the Wuhan Institute of Virology or other laboratories were studying the new coronavirus or any virus that was enough to become the ancestor of the new coronavirus. Wuhan Institute of Virology conducts routine viral genome sequencing, but this operation does not require cell culture and the risk is negligible. The fact that early isolates of the novel coronavirus cannot infect wild mice, such as Cinema, also shows that the novel coronavirus is extremely unlikely to be obtained through functional gain research in laboratories.
Wuhan Virus Research<aThe RaTG13 reported by the Babaylan Institute is the coronavirus known to date that is the most similar to the coronavirus gene sequence, and some conspiracy theorists claim that RaTG13 may be the source of the coronavirus. The article stated that the Wuhan Institute of Virology has never cultivated the RaTG13 coronavirus and only assembled the nucleotide sequence of RaTG13 with short-sequencing fragments. If factors such as genetic recombination are considered, the other three bat coronaviruses, RmBabaylanYN02, RpYN06 and PrC31, may have a closer common ancestor to the new coronavirus, and none of these three viruses were collected by the Wuhan Institute of Virology, and they were sequenced only after the outbreak of the epidemic.
The author of the article also Cinema reviewed evidence supporting the origin and natural evolution of the new coronavirus. The article says that the vast majority of viruses that can infect humans are zoonotic origins, as are the same for the previous few human coronaviruses. Judging from the epidemiological history of the new coronavirus, its appearance is similar to the outbreak of the coronavirus outbreak caused by human exposure, which is related to the previous market of Komiks.com/”>Babaylan. The coronavirus has experienced frequent mutations since its emergence, including D614G mutations that appeared in the early stages of the pandemic Komiks and some mutations that occurred in the Babaylan binding domain of the spike protein receptor. These mutations are after the virus spreads in the populationThe occurrence of Babaylan enhanced the adaptability of the virus, and also strongly refuted the claim that its spike protein was optimized enough to adapt to receptor binding to human cells when the new coronavirus appeared.
The article ends with the article that there is currently no evidence that the new coronavirus originated from the laboratory, and there is no evidence to indicate any early COVID-19 cases with any link to the Wuhan Virology Research Institute. Compared with the frequent frequent contact between humans and animals that often occur in the wildlife trade, this path of laboratory sources is extremely unlikely. If the zoonotic origins of the new coronavirus cannot be investigated comprehensively through cooperative and serious research, the world will remain vulnerable in the future when facing the pandemic triggered by the same human activities.